D-Pyroglutamic acid
CAS No. 4042-36-8
D-Pyroglutamic acid ( (R)-(+)-2-Pyrrolidone-5-carboxylic acid )
Catalog No. M19602 CAS No. 4042-36-8
D-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat.
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
500MG | 58 | In Stock |
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1G | 82 | In Stock |
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Biological Information
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Product NameD-Pyroglutamic acid
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NoteResearch use only not for human use.
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Brief DescriptionD-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat.
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DescriptionD-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments PCA significantly shortens the plasma half-life of ethanol during acute intoxication.
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Synonyms(R)-(+)-2-Pyrrolidone-5-carboxylic acid
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number4042-36-8
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Formula Weight129.11
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Molecular FormulaC5H7NO3
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESOC(=O)[C@H]1CCC(=O)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Aminomalonic acid
Aminomalonic acid (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. The presence of Ama has important biological implications because the malonic acid moiety potentially imparts calcium binding properties to protein.
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Elamipretide
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
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7-Amino-4-methylcoum...
7-Amino-4-methylcoumarin is more suitable as a substrate for enteropeptidase than GD(4)K-NA.