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D-Pyroglutamic acid
CAS No. 4042-36-8
D-Pyroglutamic acid( (R)-(+)-2-Pyrrolidone-5-carboxylic acid )
Catalog No. M19602 CAS No. 4042-36-8
D-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 58 | In Stock |
|
| 1G | 82 | In Stock |
|
Biological Information
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Product NameD-Pyroglutamic acid
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NoteResearch use only, not for human use.
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Brief DescriptionD-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat.
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DescriptionD-Pyroglutamic acid (PCA) is a cyclic derivative of glutamic acid physiologically present in mammalian tissues. It has been shown that PCA releases GABA from the cerebral cortex and displays anti-anxiety effects in a simple approach-avoidance conflict situation in the rat. In clinical pharmacology experiments PCA significantly shortens the plasma half-life of ethanol during acute intoxication.
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In Vitro——
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In Vivo——
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Synonyms(R)-(+)-2-Pyrrolidone-5-carboxylic acid
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number4042-36-8
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Formula Weight129.11
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Molecular FormulaC5H7NO3
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESOC(=O)[C@H]1CCC(=O)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Palekar AG et al. Accumulation of 50oxo-L-proline and 5-oxo-D-proline in the blood plasma in end stage renal disease. Biochem Med. 1975 Nov;14(3):339-45.
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